A two day workshop on Biostatistics (SPSS) was arranged for the final year Post Graduate students of Goa Medical College on 28 and 29 April 2015 in the laboratory of Department of Preventive and social Medicine. The Principal Faculty for this workshop was Dr. M. S. Kulkarni, Associate Professor in Statistics and Demography. This workshop was to impart the basic computer based analytical skills in Biostatistics so as to enable the researcher to complete their Post Graduate Thesis. The workshop provided the participants hands on opportunity to acquire necessary skills in Biostatistical Concepts & Analyse of their thesis data using the statistical software SPSS version 14.0. The participants at the end of the workshop will be equipped with appropriate statistical tools to complete their thesis by analyzing and interpreting their research data..

 

Dr. D. D. Motghare, Acting Dean and Prof & Head, Dept of Preventive and Social Medicine, welcomed the participants and highlighted the importance of data analysis through statistical software SPSS. These computer based skills are essential to complete and submit thesis related research work six months before the final examination. In this workshop 30 postgraduate final year students from various department participated.  Dr. M.S. Kulkarni, Principal Faculty for the workshop demonstrated the research data analysis through statistical software SPSS.  In the post evaluation survey at the end of the workshop participants expressed their satisfaction regarding learning the research data analysis skills through SPSS software 

Trimethoprim–sulfamethoxazole increases the risk of hyperkalemia when used with spironolactone. Doctors examined whether this drug combination is associated with an increased risk of sudden death, a consequence of severe hyperkalemia. 

A  population-based nested case–control study was conducted involving Ontario residents aged 66 years or older who received spironolactone between Apr. 1, 1994, and Dec. 31, 2011. Within this group, they identified cases as patients who died of sudden death within 14 days after receiving a prescription for trimethoprim–sulfamethoxazole or one of the other study antibiotics (amoxicillin, ciprofloxacin, norfloxacin or nitrofurantoin). 

Of the 11 968 patients who died of sudden death while receiving spironolactone, we identified 328 whose death occurred within 14 days after antibiotic exposure. Compared with amoxicillin, trimethoprim–sulfamethoxazole was associated with a more than twofold increase in the risk of sudden death (adjusted OR 2.46, 95% confidence interval [CI] 1.55–3.90). Ciprofloxacin (adjusted OR 1.55, 95% CI 1.02–2.38) and nitrofurantoin (adjusted OR 1.70, 95% CI 1.03–2.79) were also associated with an increased risk of sudden death, although the risk with nitrofurantoin was not apparent in a sensitivity analysis. 

The antibiotic trimethoprim–sulfamethoxazole was associated with an increased risk of sudden death among older patients taking spironolactone. When clinically appropriate, alternative antibiotics should be considered in these patients.

 

Reference

Antoniou T, Hollands S, Macdonald EM, Gomes T, Mamdani MM, Juurlink DN; et al. Trimethoprim-sulfamethoxazole and risk of sudden death among patients taking spironolactone. CMAJ. 2015 Feb 2. 

Revised Guidelines for PEP for HIV

Pls. Download click PDF here

 

 

Recognizing the successful conduct of the 28 Eye Camps in equal number of villages under the State Level NetraDeep Campaign, current Dean, Goa Medical College, Dr Pradeep G. NaikIMA Goa State Coordinator for NetraDeep Campaign (2014), & Senior IMA Tiswadi Member was bestowed the prestigious National Level IMA Outstanding Community Service Award by the National IMA Awards Committee. As a State Coordinator Dr Pradeep meticulously planned the 28 Eye Camps under the NetraDeep program, under Aao Gaon Chalen, by selecting those 28 villages that were yet unreached under the National Blindness Control Program. He was assisted by a Team of his experienced colleagues Dr Shashikant & Dr Kadambari Kulkarni, Dr Chandrakant Shetye, Dr Dipti (Sawaiker) Shrivastav, Dr Shweta Khandeparkar and ably supported by the Senior & Junior Residents from Department of Ophthalmology, alongwith expert Optometrists & Mobile Eye Care Unit of Mukta Opticians and the IMA Student Wing volunteers, besides valuable support by each of the 7 Local IMA Branches & Panchayats / NGOs. Over 5,500 patients were screened through the dedicated efforts of the entire NetraDeep Team and 4,500 were provided free spectacles and/or ophthalmic medicines sponsored by CIPLA & Proprietor of Mukta Opticians Shri Kishor Sarsolkar. Nearly 359 patients were later investigated, transported & operated for Cataracts (with IOLs), pterygium & other occular disorders at Goa Medical College. The noble work done by the NetraDeep Team to restore sight of thousands of underprivileged in rural villages under the Leadership of Dr Pradeep Naik was befittingly adjudged by the IMA Awards Committee for the Outstanding Community Service Award at National level. He received the Award at the National IMA Conference held recently in Ahmedabad, Gujarat from the National IMA President Dr Jitendra Patel & HSG Dr Narendra Saini.

 
During the Same Conference the Best Adjudged State IMA President in all States/Territories Award was presented to Dr. Jagadish A. Cacodcar, Assoc. Professor Dept of PSM, Academic I/C for his outstanding service & Leadership as State IMA President in Goa. Dr Cacodcar conducted numerous State Level CMEs, Health Education & Career Guidance Programs, besides several Community Service activities. During 2014 he was instrumental in colloborating with a number of International & National Medical Organizations like BMJ, GAPIO, SRS Global, University of South Florida, University of Tennesse and invited a number of International & National Level Speakers to educate IMA Members in Goa. Serving in various capacities as an IMA Member at IMA CQS & IMA Goa State Level since the last 19 years, Dr Jagadish has previously been Awarded Best State IMA Secretary at National Level (2007), Best Local IMA Branch President (2011) & Best Local IMA Branch Secretary (1999). He was the Editor IMA News in 1999. During the year 2014, Dr Cacodcar was also the recipient of the GAPIO Service Excellence Award at Kolkata & Dr. S. Radhakrishnan National Medical Teacher Award at New Delhi.

The new antibiotic, teixobactin, has proven effective against a number of bacterial infections that have developed resistance to existing antibiotic drugs.

Researchers have used teixobactin to cure lab mice of MRSA (methicillin-resistant Staphylococcus aureus), a bacterial infection that affects  80,000 Americans and kills 11,000 every year, according to the U.S. Centers for Disease Control and Prevention (CDC). The new antibiotic also worked against the bacteria that cause pneumococcal pneumonia. Cell culture tests also showed that the new drug effectively killed off drug-resistant strains of tuberculosis, anthrax and Clostridium difficile.

Teixobactin inhibits cell wall synthesis by binding to a highly conserved motif of lipid II (precursor of peptidoglycan) and lipid III (precursor of cell wall teichoic acid).

 

Reference

Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, et al. A new antibiotic kills pathogens  without detectable resistance. Nature.2015 Jan 22;517(7535):455-9.